منابع مشابه
Op-brai130036 1216..1230
Cocaine seeking behaviour and relapse have been linked to impaired potentiation and depression at excitatory synapses in the nucleus accumbens, but the mechanism underlying this process is poorly understood. We show that, in the rat nucleus accumbens core, D-serine is the endogenous coagonist of N-methyl-D-aspartate receptors, and its presence is essential for N-methyl-D-aspartate receptor-depe...
متن کاملC0lc00585a 1342..1350
In this work we report on the design, microfabrication and analytical performances of a new electrochemical sensor array (ESA) which allows for the first time the simultaneous amperometric detection of nitric oxide (NO) and peroxynitrite (ONOO ), two biologically relevant molecules. The on-chip device includes individually addressable sets of gold ultramicroelectrodes (UMEs) of 50 mm diameter, ...
متن کاملDmd051714 1220..1230
Prilocaine and lidocaine are classified as amide-type local anesthetics for which serious adverse effects include methemoglobinemia. Although the hydrolyzed metabolites of prilocaine (o-toluidine) and lidocaine (2,6-xylidine) have been suspected to induce methemoglobinemia, the metabolic enzymes that are involved remain uncharacterized. In the present study, we aimed to identify the human enzym...
متن کامل1224-1230 Giraldo LAJP 3159:Giraldo
1 Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, A.A. 14490, Bogotá, D.C, Colombia. 571-3165000 ext. 14662 2 Instituto Universitario de Bio-Orgánca “Antonio González”, Universidad de La Laguna, Avda. Astrofísico. Francisco Sánchez 2, La Laguna, 38206, Tenerife, Islas Canarias, España 3 Instituto de Química y Fisicoquímica Biológicas, Facultad de Farmacia y Bio...
متن کامل1230 Synthesis and Secretion of Lysozyme
In 1922 Alexander Fleming described the remarkable bacteriolytic activity of an enzyme, lysozyme, which was widely distributed in tissues and secretions (1). Lysozyme (muramidase) is a cationic enzyme, tool wt 14,307, which hydrolyses N-acetyl muramic /3-1, 4 N-acetyl glucosamine linkages in the bacterial cell wall (2). Although a great deal is known about its structure and enzymology its funct...
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ژورنال
عنوان ژورنال: Hispania
سال: 2001
ISSN: 1988-8368,0018-2141
DOI: 10.3989/hispania.2001.v61.i208.295